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1

Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications

Wicki, Andreas, Witzigmann, Dominik, Balasubramanian, Vimalkumar, Huwyler, Jörg

Journal:

Journal of Controlled Release

Année:

2015

Langue:

english

Fichier:

PDF, 953 KB

english, 2015

2

Lipid-polymer hybrid nanoparticles for controlled delivery of hydrophilic and lipophilic doxorubicin for breast cancer therapy

Tahir, Nayab, Madni, Asadullah, Correia, Alexandra, Rehman, Mubashar, Balasubramanian, Vimalkumar, Khan, Muhammad Muzamil, Santos, Hélder A

Journal:

International Journal of Nanomedicine

Année:

2019

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2019

3

Lipid-Polymer Hybrid Nanoparticles for Controlled Delivery of Hydrophilic and Lipophilic Doxorubicin for Breast Cancer Therapy [Erratum]

Tahir, Nayab, Madni, Asadullah, Correia, Alexandra, Rehman, Mubashar, Balasubramanian, Vimalkumar, Khan, Muhammad Muzamil, Santos, HÃ©lder A

Journal:

International Journal of Nanomedicine

Année:

2020

Langue:

english

Fichier:

PDF, 460 KB

english, 2020

4

Enzymatic Cascade Reactions inside Polymeric Nanocontainers: A Means to Combat Oxidative Stress

Pascal Tanner, Dr. Ozana Onaca, Vimalkumar Balasubramanian, Prof. Wolfgang Meier, Priv. Doz. Dr. Cornelia G. Palivan

Journal:

Chemistry - A European Journal

Année:

2011

Langue:

english

Fichier:

PDF, 554 KB

english, 2011

5

Global Structure–Activity Analysis in Drug Development Illustrated for Active Cu/Zn Superoxide Dismutase Mimics

Cornelia G. Palivan, Vimalkumar Balasubramanian, Bernard A. Goodman

Journal:

European Journal of Inorganic Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 205 KB

english, 2009

6

SOD Antioxidant Nanoreactors: Influence of Block Copolymer Composition on the Nanoreactor Efficiency

Ozana Onaca, David W. Hughes, Vimalkumar Balasubramanian, Mariusz Grzelakowski, Wolfgang Meier, Cornelia G. Palivan

Journal:

Macromolecular Bioscience

Année:

2010

Langue:

english

Fichier:

PDF, 320 KB

english, 2010

7

Biocompatible Functionalization of Polymersome Surfaces: A New Approach to Surface Immobilization and Cell Targeting Using Polymersomes

Egli, Stefan, Nussbaumer, Martin G., Balasubramanian, Vimalkumar, Chami, Mohamed, Bruns, Nico, Palivan, Cornelia, Meier, Wolfgang

Journal:

Journal of the American Chemical Society

Année:

2011

Langue:

english

Fichier:

PDF, 4.06 MB

english, 2011

8

Can polymeric vesicles that confine enzymatic reactions act as simplified organelles?

Pascal Tanner, Stefan Egli, Vimalkumar Balasubramanian, Ozana Onaca, Cornelia G. Palivan, Wolfgang Meier

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 404 KB

english, 2011

9

A surprising system: polymeric nanoreactors containing a mimic with dual-enzyme activity

Balasubramanian, Vimalkumar, Onaca, Ozana, Ezhevskaya, Maria, Van Doorslaer, Sabine, Sivasankaran, Balasubramanian, Palivan, Cornelia G.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 804 KB

english, 2011

10

Aiding Nature’s Organelles: Artificial Peroxisomes Play Their Role

Tanner, Pascal, Balasubramanian, Vimalkumar, Palivan, Cornelia G.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 4.41 MB

english, 2013

11

Water-Soluble Co(III) Complexes of Substituted Phenanthrolines with Cell Selective Anticancer Activity

Jagadeesan, Sivaraman, Balasubramanian, Vimalkumar, Baumann, Patric, Neuburger, Markus, Häussinger, Daniel, Palivan, Cornelia G.

Journal:

Inorganic Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 3.53 MB

english, 2013

12

Structural characterization of a highly active superoxide-dismutase mimic

Balasubramanian, Vimalkumar, Ezhevskaya, Maria, Moons, Hans, Neuburger, Markus, Cristescu, Carol, Van Doorslaer, Sabine, Palivan, Cornelia

Journal:

Physical Chemistry Chemical Physics

Année:

2009

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2009

13

Polymersomes conjugated to 83-14 monoclonal antibodies: Invitro targeting of brain capillary endothelial cells

Dieu, Le-Ha, Wu, Dalin, Palivan, Cornelia G., Balasubramanian, Vimalkumar, Huwyler, Jörg

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Année:

2014

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2014

14

On-Chip Self-Assembly of a Smart Hybrid Nanocomposite for Antitumoral Applications

Herranz-Blanco, Bárbara, Liu, Dongfei, Mäkilä, Ermei, Shahbazi, Mohammad-Ali, Ginestar, Eloy, Zhang, Hongbo, Aseyev, Vladimir, Balasubramanian, Vimalkumar, Salonen, Jarno, Hirvonen, Jouni, Santos, Hél

Journal:

Advanced Functional Materials

Année:

2015

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2015

15

Drug Delivery: On-Chip Self-Assembly of a Smart Hybrid Nanocomposite for Antitumoral Applications (Adv. Funct. Mater. 10/2015)

Herranz-Blanco, Bárbara, Liu, Dongfei, Mäkilä, Ermei, Shahbazi, Mohammad-Ali, Ginestar, Eloy, Zhang, Hongbo, Aseyev, Vladimir, Balasubramanian, Vimalkumar, Salonen, Jarno, Hirvonen, Jouni, Santos, Hél

Journal:

Advanced Functional Materials

Année:

2015

Fichier:

PDF, 1.84 MB

2015

16

Biocompatible Polymer–Peptide Hybrid-Based DNA Nanoparticles for Gene Delivery

Witzigmann, Dominik, Wu, Dalin, Schenk, Susanne H., Balasubramanian, Vimalkumar, Meier, Wolfgang, Huwyler, Jörg

Journal:

ACS Applied Materials & Interfaces

Année:

2015

Langue:

english

Fichier:

PDF, 3.18 MB

english, 2015

17

Multifaceted Polymersome Platforms: Spanning from Self-assembly To Drug Delivery and Protocells

Balasubramanian, Vimalkumar, Herranz-Blanco, Bárbara, Almeida, Patrick V., Hirvonen, Jouni, Santos, Hélder A.

Journal:

Progress in Polymer Science

Année:

2016

Langue:

english

Fichier:

PDF, 518 KB

english, 2016

18

pH-Switch Nanoprecipitation of Polymeric Nanoparticles for Multimodal Cancer Targeting and Intracellular Triggered Delivery of Doxorubicin

Herranz-Blanco, Bárbara, Shahbazi, Mohammad-Ali, Correia, Alexandra R., Balasubramanian, Vimalkumar, Kohout, Tomáš, Hirvonen, Jouni, Santos, Hélder A.

Journal:

Advanced Healthcare Materials

Année:

2016

Langue:

english

Fichier:

PDF, 3.18 MB

english, 2016

19

Angiopep2-functionalized Polymersomes for Targeted Doxorubicin Delivery to Glioblastoma Cells

Figueiredo, Patrícia, Balasubramanian, Vimalkumar, Shahbazi, Mohammad-Ali, Correia, Alexandra, Wu, Dalin, Palivan, Cornelia G., Hirvonen, Jouni T., Santos, Hélder A.

Journal:

International Journal of Pharmaceutics

Année:

2016

Langue:

english

Fichier:

PDF, 3.79 MB

english, 2016

20

Targeted Cancer Therapy: pH-Switch Nanoprecipitation of Polymeric Nanoparticles for Multimodal Cancer Targeting and Intracellular Triggered Delivery of Doxorubicin (Adv. Healthcare Mater. 15/2016)

Herranz-Blanco, Bárbara, Shahbazi, Mohammad-Ali, Correia, Alexandra R., Balasubramanian, Vimalkumar, Kohout, Tomáš, Hirvonen, Jouni, Santos, Hélder A.

Journal:

Advanced Healthcare Materials

Année:

2016

Fichier:

PDF, 2.87 MB

2016

21

Active diffusion of nanoparticles of maternal origin within the embryonic brain

Yuryev, Mikhail, Ferreira, Mónica PA, Balasubramanian, Vimalkumar, Correia, Alexandra MR, Mäkilä, Ermei M, Jokinen, Ville, Andriichuk, Liliia, Kemell, Marianna, Salonen, Jarno J, Hirvonen, Jouni T, Sa

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 4.77 MB

english, 2016

22

Quercetin-Based Modified Porous Silicon Nanoparticles for Enhanced Inhibition of Doxorubicin-Resistant Cancer Cells

Liu, Zehua, Balasubramanian, Vimalkumar, Bhat, Chinmay, Vahermo, Mikko, Mäkilä, Ermei, Kemell, Marianna, Fontana, Flavia, Janoniene, Agne·, Petrikaite, Vilma, Salonen, Jarno, Yli-Kauhaluoma, Jari, Hir

Journal:

Advanced Healthcare Materials

Année:

2017

Langue:

english

Fichier:

PDF, 3.27 MB

english, 2017

23

Polymersomes containing quantum dots for cellular imaging

Huwyler, Jörg, Camblin, Marine, Detampel, Pascal, Kettiger, Helene, Wu, Dalin, Balasubramanian, Vimalkumar

Journal:

International Journal of Nanomedicine

Année:

2014

Langue:

english

Fichier:

PDF, 2.78 MB

english, 2014

24

Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-Like Functions

Balasubramanian, Vimalkumar, Correia, Alexandra, Zhang, Hongbo, Fontana, Flavia, Mäkilä, Ermei, Salonen, Jarno, Hirvonen, Jouni, Santos, Hélder A.

Journal:

Advanced Materials

Année:

2017

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2017

25

Nanoreactors: Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-Like Functions (Adv. Mater. 11/2017)

Balasubramanian, Vimalkumar, Correia, Alexandra, Zhang, Hongbo, Fontana, Flavia, Mäkilä, Ermei, Salonen, Jarno, Hirvonen, Jouni, Santos, Hélder A.

Journal:

Advanced Materials

Année:

2017

Fichier:

PDF, 2.67 MB

2017

26

Bridging the Knowledge of Different Worlds to Understand the Big Picture of Cancer Nanomedicines

Balasubramanian, Vimalkumar, Liu, Zehua, Hirvonen, Jouni, Santos, Hélder A.

Journal:

Advanced Healthcare Materials

Année:

2017

Langue:

english

Fichier:

PDF, 3.31 MB

english, 2017

27

Drug-Loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling

Ferreira, Mónica P. A., Ranjan, Sanjeev, Kinnunen, Sini, Correia, Alexandra, Talman, Virpi, Mäkilä, Ermei, Barrios-Lopez, Brianda, Kemell, Marianna, Balasubramanian, Vimalkumar, Salonen, Jarno, Hirvon

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 3.11 MB

english, 2017

28

Drug Delivery: Drug-Loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling (Small 33/2017)

Ferreira, Mónica P. A., Ranjan, Sanjeev, Kinnunen, Sini, Correia, Alexandra, Talman, Virpi, Mäkilä, Ermei, Barrios-Lopez, Brianda, Kemell, Marianna, Balasubramanian, Vimalkumar, Salonen, Jarno, Hirvon

Journal:

Année:

2017

Fichier:

PDF, 6.32 MB

2017

29

Development and optimization of methotrexate-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery applications

Tahir, Nayab, Madni, Asadullah, Balasubramanian, Vimalkumar, Rehman, Mubashar, Correia, Alexandra, Kashif, Prince Muhammad, Mäkilä, Ermei, Salonen, Jarno, Santos, Hélder A.

Journal:

International Journal of Pharmaceutics

Année:

2017

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2017

30

Cell Membranes based Nanoreactor to Mimic the Bio-Compartmentalization Strategy of a Cell

Balasubramanian, Vimalkumar, Poillucci, Andrea, Correia, Alexandra, Zhang, Hongbo, Celia, Christian, Santos, Hélder A.

Journal:

ACS Biomaterials Science & Engineering

Année:

2018

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2018

31

Engineered antibody-functionalized porous silicon nanoparticles for therapeutic targeting of pro-survival pathway in endogenous neuroblasts after stroke

Balasubramanian, Vimalkumar, Domanskyi, Andrii, Renko, Juho-Matti, Sarparanta, Mirkka, Wang, Chang-Fang, Correia, Alexandra, Mäkilä, Ermei, Alanen, Osku S., Salonen, Jarno, Airaksinen, Anu J., Tuomine

Journal:

Année:

2020

Langue:

english

Fichier:

PDF, 2.78 MB

english, 2020

32

Systematic In Vitro Biocompatibility Studies of Multimodal Cellulose Nanocrystal and Lignin Nanoparticles

Imlimthan, Surachet, Correia, Alexandra, Figueiredo, Patrícia, Lintinen, Kalle, Balasubramanian, Vimalkumar, Airaksinen, Anu J., Kostiainen, Mauri A., Santos, Hélder A., Sarparanta, Mirkka

Journal:

Journal of Biomedical Materials Research Part A

Année:

2019

Langue:

english

Fichier:

PDF, 2.82 MB

english, 2019

33

Systematic In Vitro Biocompatibility Studies of Multimodal Cellulose Nanocrystal and Lignin Nanoparticles

Imlimthan, Surachet, Correia, Alexandra, Figueiredo, Patrícia, Lintinen, Kalle, Balasubramanian, Vimalkumar, Airaksinen, Anu J., Kostiainen, Mauri A., Santos, Hélder A., Sarparanta, Mirkka

Journal:

Journal of Biomedical Materials Research Part A

Année:

2019

Fichier:

PDF, 2.82 MB

2019

34

Evaluation of the effects of nanoprecipitation process parameters on the size and morphology of poly(ethylene oxide)-block-polycaprolactone nanostructures

KÃ¤nkÃ¤nen, Voitto, Seitsonen, Jani, Tuovinen, Henri, Ruokolainen, Janne, Hirvonen, Jouni, Balasubramanian, Vimalkumar, Santos, HÃ©lder A.

Journal:

International Journal of Pharmaceutics

Année:

2020

Fichier:

PDF, 4.60 MB

2020